I am part of the ASKE Yeast Group of researchers from Adelaide, Southampton, Kent, and Essex (ASKE), who study mathematical and experimental models for yeast colony growth. Our interdisciplinary team aims to understand the fundamental mechanisms of yeast growth, and how they give rise to colony-scale spatial patterns. We study strains of the baker’s yeast S. cerevisiae, a model organism of medical and technological importance, and of C. albicans, a major fungal pathogen. We apply a variety of mathematical techniques, including agent-based modelling, reaction—diffusion models, image processing, and parameter inference.
Publications
- H Tronnolone, AKY Tam, Z Szenczi, JEF Green, S Balasuriya, EL Tek, JM Gardner, JF Sundstrom, V Jiranek, SG Oliver and BJ Binder, Diffusion-limited growth of microbial colonies, Sci. Rep. 8 (2018), 5992, DOI: 10.1038/s41598-018-23649-z.
- K Li, JEF Green, H Tronnolone, AKY Tam, AJ Black, JM Gardner, JF Sundstrom, V Jiranek and BJ Binder, An off-lattice discrete model to characterise filamentous yeast colony morphology, PLOS Comput. Biol. 20 (2024), e1012605, DOI: 10.1371/journal.pcbi.1012605. [PDF]
- K Li, AJ Black, T Knežević, JM Gardner, J Zhang, V Jiranek, JEF Green, BJ Binder and AKY Tam, Modelling the emergence of spiral colony morphology in the yeast Magnusiomyces magnusii, bioRxiv (2025), DOI: 10.1101/2025.09.07.674689. Submitted to ANZIAM J. [PDF]
- K Li, AKY Tam, JM Gardner, JF Sundstrom, V Jiranek, JEF Green, BJ Binder and AJ Black, Agent-based modelling and time series inference of filamentous yeast colonies, bioRxiv (2025), DOI: 10.1101/2025.09.07.674689. Submitted to J. R. Soc. Interface. [PDF]
- K Li, S Skivens, JEF Green, AKY Tam, DR Pentland, H Baumann, CW Gourlay, BJ Binder, PP Laissue, Multiscale analysis of Candida albicans biofilm development, bioRxiv (2025), DOI: 10.1101/2025.09.18.677201. Submitted to Biofilm. [PDF]
Collaborators